Intoxications par les plantes et les produits de la pharmacopée traditionnelle chez l’enfant

Introduction: Plants are at the cause of many serious poisonings, especially among children; they are usually either accidental or secondary to a therapeutic use. Objectives: -To put the light on the frequency of acute plant poisoning among children. -To describe the clinical, the analytical and the therapeutic, socio demographic characteristics of this type of poisoning. -To propose Preventive measures that are adapted to our context. Materials and methods: This is a retrospective study of poisoning cases, of both plants and traditional pharmacopeia products among children under the age of 15, that were identified at the toxicology laboratory of the University Hospital (CHU) of Fez, from January 2012 to June 2014. Results: As a result, 30 cases were admitted for the management of poisonings, either by plants or by products of traditional pharmacopeia. The average age of our patients was 6, 1+/-5,4 with the highest values of 1 month to 15 years (12G, 18B, SR = 1.5). In fact the Thistle glue was the most incriminated plant (30%) followed by the Cade oil (23.3%), and then the Mkhinza (13.3%), and 30% of these cases include collective poisonings. Besides the intoxication was accidental in 86,7 % of cases, while 6.7% of them were self-induced. AT their admission, all the patients presented in 53,3 % of cases, followed by cardio vascular signs in 46.7 % of them, and even respiratory distress in 16.6% of the cases. The toxicological test was carried out for 22 cases, with positive results in 11 cases. Furthermore, the treatment was mainly symptomatic; however, a specific treatment was needed, using the N-Acetyl-Cysteine, for 10 children. Then, the progression was propitious, associated with 7 deaths and a case fatality rate of 23.3% especially related to the Thistle glue and Mixture. Conclusion: Among children, poisonings by plants and by other products of traditional pharmacopeia, whether under accident circumstances or for a therapeutic use, are responsible for a high fatality rate. Further, the decrease of this poisoning type requires preventive measures based on large public awareness and the implantation of an antitoxic strategy that would be adopted to our context

Référence1428
Année2014
TypeThèse
Lien document
AuteurHafidi K
DisciplineLaboratoire
EncadrantAchour S