Plasmacytoid Dendritic Cells Leukemia: a rare presentation.

The plasmacytoid dendritic cells leukemia is a rare hematolymphoid neoplasm with a very poor prognosis, where skin involvement is common. It is a malignant proliferation developed at the expense of hematopoietic cells of the white blood cells, proximate to normal plasmacytoid dendritic cells. The phenotype of tumor cells initially described was CD4 + CD56 +, without T marker expression. CD56- forms have also been reported, even fewer without skin involvement. More specific markers are expressed by tumor cells: CD123, BDCA2, BDCA4. We report an unusual presentation of this entity, but without skin lesions. The diagnosis of plasmacytoid dendritic cells leukemia was made on the cytological and immunophenotypic data given

Référence2483
Année2014
TypeArticle
Lien document
Lien externehttp://www.esciencecentral.org/journals/plasmocytoid-dendritic-cells-leukemia-a-rare-presentation-2329-6917.1000131.php?aid=26692
Disciplines associéesHôpital Militaire My Ismail Meknès
AuteurTlamcani I
Auteurs associésYahyaoui G, Hassani MA, Benjelloun S, Benseddik N
DisciplineLaboratoire
RevueJournal of Leukemia
Référence Revue2329-6917