The plasmacytoid dendritic cells leukemia is a rare hematolymphoid neoplasm with a very poor prognosis, where skin involvement is common. It is a malignant proliferation developed at the expense of hematopoietic cells of the white blood cells, proximate to normal plasmacytoid dendritic cells. The phenotype of tumor cells initially described was CD4 + CD56 +, without T marker expression. CD56- forms have also been reported, even fewer without skin involvement. More specific markers are expressed by tumor cells: CD123, BDCA2, BDCA4. We report an unusual presentation of this entity, but without skin lesions. The diagnosis of plasmacytoid dendritic cells leukemia was made on the cytological and immunophenotypic data given
Référence | 2483 |
Année | 2014 |
Type | Article |
Lien document | |
Lien externe | http://www.esciencecentral.org/journals/plasmocytoid-dendritic-cells-leukemia-a-rare-presentation-2329-6917.1000131.php?aid=26692 |
Disciplines associées | Hôpital Militaire My Ismail Meknès |
Auteur | Tlamcani I |
Auteurs associés | Yahyaoui G, Hassani MA, Benjelloun S, Benseddik N |
Discipline | Laboratoire |
Revue | Journal of Leukemia |
Référence Revue | 2329-6917 |