Systemic lupus erythematosus (SLE) and small-sized vessel vasculitis are usually two distinguishable
autoimmune diseases. We report a case of novo SLE associated with cytoplasmatic antineutrophil
cytoplasmatic antibodies (c-ANCA). A 34-year old woman was admitted to our hospital for purpura, weight
loss, inflammatory polyarthralgia and nasal stuffiness with advanced renal failure. The investigations have
revealed positive immunological test (ANN, anti-DNA and c-ANCA). Renal biopsy showed a diffuse
proliferative lupus nephritis (class IV-G (A)) with necrotizing crescentic glomerulonephritis. We have
retained the diagnosis of SLE associated to c-ANCA. She has received corticosteroids and
cyclophosphamide. The evolution was marked by the occurrence of alveolar hemorrhage that caused her
death
| Référence | 2504 |
| Année | 2014 |
| Type | Article |
| Lien document | |
| Lien externe | http://internationalscholarsjournals.org/download.php?id=900329344942171390.pdf&type=application/pdf&op=1 |
| Auteur | El Youbi R |
| Auteurs associés | Arrayhani M, Sqalli T |
| Discipline | Néphrologie |
| Revue | Journal of Medical Case Reports |
| Référence Revue | 2(2):022-023 |
