Summary
Introduction: In developed countries, reinfection after successful eradication of Helicobacter
pylori appears unusual. High prevalences of H. pylori in developing countries may result in
high reinfection rates. In Morocco, published studies regarding the prevalence of H. pylori are
limited, and to our knowledge, there are no data regarding the reinfection rate of H. pylori
after successful treatment.
Aim: The aim of this study was to determine the prevalence of H. pylori in our area, and the
reinfection rate at 6 months and 1 year of follow-up after successful eradication.
Methods: Consecutive patients with investigated ulcer or non-ulcer dyspepsia were prospectively
enrolled in the Hassan II University Hospital of Fez. Patients with H. pylori infection were
treated with a 1-week triple therapy or 10 day sequential therapy. Those tested urea breath test
negative after 3 months of treatment were followed prospectively with repeated urea breath
test at 6 months and 1 year. H. pylori status at endoscopic examination was determined by rapid
urease test, histology, and culture.
Results: Four hundred and twenty-nine patients were enrolled in the study, among them 324
patients (75.5%) presented with H. pylori infection. Two hundred and fifty-six (83.3%) patients
had successfully eradicated H. pylori following treatment, among them, two patients (0.8%)
were reinfected with H. pylori over 12 months. The rate of reinfection was 0.42% in the first 6
months and of 0.45% in the first year of the study
| Référence | 2820 |
| Année | 2013 |
| Type | Article |
| Lien document | |
| Lien externe | http://www.sciencedirect.com/science/article/pii/S2210740113000399 |
| Disciplines associées | Laboratoire |
| Auteur | Benajah d A |
| Auteurs associés | Lahbabi M, Alaoui S, El rhazi K, El abkari M, Nejjari C, Amarti A, Bennani B, Mahmoud M, Ibrahimi SA |
| Discipline | Gastroentérologie |
| Revue | Clin Res Hepatol Gastroenterol. |
| Référence Revue | 37(5):519-26 |
