Interruption in tuberculosis (TB) treatment still remains the most important challenge for control of the disease. This study aimed to identify the determinants of TB treatment default in Fez, Morocco. A 1:2 pair-matched case-control study was carried out in the TB control units in Fez. Cases were defaulters to TB treatment and were matched by age and sex to non-defaulters (controls). Of the 320 patients (108 defaulters, 212 controls), 80.6% were male. The main reason for defaulting reported by patients was the sensation of being cured. Predictive factors for treatment default in the multivariate conditional logistic regression analysis, were: relapsed case (adjusted OR = 4.49; 95% Cl: 1.87-10.8), current smoking (aOR= 2.10; 95% Cl: 1.07-4.14), alcohol use (aOR = 2.92; 95% Cl: 1.04-8.19), being more than 30 minutes away from the health centre (aOR = 3.34; 95% Cl: 1.06-10.5) and perception of having received insufficient explanation about the disease (aOR = 2.87; 95% CI: 1.53-5.36). The rate of defaulting in Fez can be lowered through targeted and realistic measures
| Référence | 2925 |
| Année | 2013 |
| Type | Article |
| Lien externe | https://www.ncbi.nlm.nih.gov/pubmed/24975352 |
| Disciplines associées | Faculté de Médecine et de Pharmacie de Fès |
| Auteur | Katia Slama |
| Auteurs associés | Tachfouti N, Obtel M, Nejjari C |
| Discipline | Epidémiologie |
| Revue | East Mediterr Health J. |
| Référence Revue | 19(8):687-93 |