Chronic inflammatory joint disease revealing leprosy

. Introduction
Mycobacterium leprae, the organism that causes leprosy, was described by Hansen in 1873. Leprosy is a chronic granulomatous disease with two main presentations, tuberculoid leprosy and lepromatous leprosy. Tuberculoid leprosy manifests as skin lesions and neurological impairments. Lepromatous leprosy is a less common but more severe disease in which skin erosions develop over the face, limbs, and torso; in addition, the mucous membranes and internal organs are affected [1] and [2]. Between these two poles, a broad variety of borderline forms exist, attesting to the considerable interindividual variability in immune responses to M. leprae [3]. Musculoskeletal manifestations occur chiefly during lepra reactions [4]. They may mimic a chronic inflammatory joint disease, delaying the diagnosis [5], as illustrated by our case-report

Référence2718
Année2014
TypeArticle
Lien document
Lien externehttp://www.sciencedirect.com/science/article/pii/S1297319X05001223?np=y
AuteurEl Ouazzani FZ
Auteurs associésTahiri L, Harzy T
DisciplineRhumatologie
RevueJoint Bone Spine
Référence Revue73(3):314-317