CANCER DE LA VESICULE BILIAIRE (A propos de 53 cas)

INTRODUCTION:

The cancer of the gall bladder is placed at the 5th rank of digestive cancers. It is a relatively rare cancer but whose forecast remains frightening. Several risk factors are accused, whose main thing is the biliary lithiasis. This cancer poses the early problem of diagnosis because of a vague and nonspecific symptomatology. The surgery, when it is possible, is the only curative treatment.

MATERIALS AND METHODS:

This is a retrospective study of 53 cases of primary cancer of the gallbladder collected to surgery visceral A and B CHU Hassan II Fez over a period of 5 years (January 2009 – December 2013). For this study, we identified and analyzed the following parameters: Epidemiological data, circumstances of diagnosis, paraclinical and histological data and the treatments performed. RESULTS: The median age of our patients was 61.5 years with a clear female prevalence (75.5%). The bladder-like lithiasis is the independent factor of risk. Clinical symptomatology was not specific. It was dominated by the pain of the hypochondre right (72%) and the jaundice (39.6%). Echography is the examination of first intention, it evoked the diagnosis in 50.9% of the cases. The scanner made it possible to suspect the diagnosis in 87,2% of the cases. In 22.6% of the cases, the cancer of the gall bladder was discovered in a fortuitous way after examination anatomopathologic of the parts of cholecystectomy. 26.3% of the interventions were carried out with curative aiming, against 41.5% with palliative aiming.

CONCLUSION:

The gall bladder cancer is the most common cancer of the bile.Treatment is based on surgical resection feasible in less than 30% of patients due to the often advanced tumors at diagnosis character. Its prognosis is poor. Advances in endoscopy and interventional radiology have improved palliative care for these patients.