Introduction: Sweet’s syndrome is an acute neutrophilic dermatosis characterized by a diffuse dermal infiltrate of
mature neutrophils. In most cases, it occurs as an isolated phenomenon (idiopathic Sweet’s syndrome) but it can
be drug induced or associated with a variety of underlying diseases such as infections, neoplasms, and chronic
inflammatory diseases. The association between Sweet’s syndrome and ankylosing spondylitis is rare. Only a few
cases have been reported in the literature. We report a new case in which we describe an outbreak of acute
neutrophilic dermatosis revealing ankylosing spondylitis.
Case presentation: A 33-year-old Moroccan man presented with large-joint polyarthralgia, inflammatory pain in his
buttocks and lower lumbar spine, fever and skin lesions. On examination, the patient had a low-grade fever, six
tender but not swollen joints, limitation of motion of the lumbar spine, and painful erythematous maculopapules
over his face, neck, and hands. Laboratory tests showed hyperleukocytosis, and elevated erythrocyte sedimentation
rate and C-reactive protein. The immunological tests and infectious disease markers were negative. Investigations
for an underlying neoplastic disease remained negative. Magnetic resonance imaging showed a bilateral sacroiliitis.
Skin biopsy findings were consistent with Sweet’s syndrome. The diagnosis of Sweet’s syndrome associated with
ankylosing spondylitis was established. Nonsteroid anti-inflammatory drugs were started and the patient showed
rapid clinical and biological improvement.
Conclusion: Three observations of the association between Sweet’s syndrome and spondylarthropathy have been
reported in the literature. The cause of this association remains unclear. Some hypotheses have been developed,
but further studies are needed to confirm or refute them
| Référence | 2905 |
| Année | 2013 |
| Type | Article |
| Lien document | |
| Lien externe | http://europepmc.org/articles/PMC3564777 |
| Disciplines associées | Dermatologie, Radiologie Centrale |
| Auteur | Mansouri S |
| Auteurs associés | Abourazzak FZ, Aradoini N, Bettioui A, Fourtassi M, Tahiri L, Mernissi F.-Z, Tizniti S, Harzy T |
| Discipline | Rhumatologie |
| Revue | Journal of Medical Case Reports |
| Référence Revue | 0,302777778 |
