Abstract
Primary angiosarcoma of the breast is extremely rare. Radiologic findings are often non specific and may appear
completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the
high rates of local recurrence and early development of metastasis. Surgical removal followed by adjuvant
chemotherapy seems improve the prognosis.
We report a case of a 33- year-old woman with a highly vascular mass in her right breast which is suggestive of
malignancy at radiology. Initial core needle biopsy showed a benign hemangioma. The patient underwent a
mastectomy. The tumor histology showed papillary formations and vascular structures lined by atypical cells with
hyperchromatic nucleus and eosinophilic cytoplasm with solid areas. The tumor cells expressed CD34 and CD31
but were negative for cytokeratin. The diagnosis of angiosarcoma grade III was made. The patient is now receiving
chemotherapy. She is still alive